When should I take Soliqua
Mia Kelly
Published Mar 23, 2026
You should inject your Soliqua (insulin glargine and lixisenatide) dose within one hour before your first meal of the day, which for most people will be in the morning before breakfast. If you need to use Soliqua at night, speak with your doctor, who may be able to help you adjust your medication schedule.
How long does Soliqua take to work?
Soliqua starts to lower levels of glucose (sugar) in the blood two hours after injection and keeps working evenly for 20 to 24 hours in most patients.
Is Soliqua fast acting?
Soliqua 100/33 contains a combination of insulin glargine and lixisenatide. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.
Does Soliqua make you lose weight?
Weight gain is not a common side effect for Soliqua (insulin glargine/lixisenatide). In some clinical studies, patients using Soliqua had an average weight loss of 0.1 and 0.3 kg (0.2 and 0.7 lb). In contrast, patients using only insulin glargine (Lantus) had a weight gain of 1.1 and 2 kg (2.6 and 4.4 lb).Does Soliqua need to be refrigerated after opening?
Storing your SOLIQUA 100/33 pen Before you use your pen for the first time: Store with cap on in original packaging. Refrigerate between 36°F and 46°F (2°C and 8°C). Do not freeze.
What are the side effects of Soliqua?
- low blood sugar (hypoglycemia),
- allergic reactions,
- nausea,
- runny or stuffy nose,
- diarrhea,
- upper respiratory tract infection,
- headache,
- injection site reactions (swelling, redness, itching, pain, skin discoloration, warmth, and a hard lump),
Should Soliqua be taken in the morning or at night?
You should inject your Soliqua (insulin glargine and lixisenatide) dose within one hour before your first meal of the day, which for most people will be in the morning before breakfast. If you need to use Soliqua at night, speak with your doctor, who may be able to help you adjust your medication schedule.
Is Soliqua better than Lantus?
It showed that Soliqua 100/33 may work slightly better than Lantus for decreasing hemoglobin A1c (HbA1c), but not as well in reducing fasting blood sugar levels. After 30 weeks of treatment, Soliqua 100/33 reduced HbA1c by 1.1 percent, and fasting blood sugar levels by 5.7 mg/dL.Can Soliqua cause pancreatitis?
Cases of pancreatitis were reported in clinical trials of lixisenatide. After initiation of SOLIQUA 100/33, observe patients for signs and symptoms of pancreatitis (e.g., persistent severe abdominal pain, sometimes radiating to the back and which may be accompanied by vomiting).
Is diarrhea a side effect of Soliqua?Nausea and diarrhea usually happen more frequently when you start using SOLIQUA 100/33, but often lessen within two weeks. In fact, based on a pooled analysis of the safety population (834 patients) for SOLIQUA 100/33, 1.0-1.1% of patients stopped using SOLIQUA 100/33 due to upset stomach, nausea, or diarrhea.
Article first time published onHow much Soliqua should I take?
The recommended starting dosage of SOLIQUA 100/33 is 30 units (30 units insulin glargine/10 mcg lixisenatide) given subcutaneously once daily.
Can you take Soliqua and Lantus together?
Can you take Lantus and Soliqua together? No, you should not take Lantus and Soliqua together. Both contain insulin glargine and you could easily inject yourself with too much insulin.
What tier drug is Soliqua?
Medicare prescription drug plans typically list Soliqua 100/33 on Tier 3 of their formulary. Generally, the higher the tier, the more you have to pay for the medication.
Where can I inject Soliqua?
Inject your SOLIQUA 100/33 dose exactly as your healthcare provider has shown you. Inject your SOLIQUA 100/33 dose under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdo- men).
How long is Soliqua good for out of the fridge?
Do not freeze Soliqua 100/33 pens and do not use Soliqua 100/33 if it has been frozen. After your first use, you can store your Soliqua 100/33 pen at room temperature no higher than 77°F (25°C) for up to 28 days. After 28 days, throw it away, even if there is some medicine left in the pen.
Does Soliqua expire?
After first use, use the SOLIQUA 100/33 pen for up to 28 days. Throw away the used SOLIQUA 100/33 pen after 28 days, even if there is some medicine left in the pen. Do not use SOLIQUA 100/33 past the expiration date printed on the label of the carton and pen.
How do you use a Soliqua 100 50?
Soliqua should be injected once a day within one hour prior to a meal. It is preferable that the prandial injection is performed before the same meal everyday, when the most convenient meal has been chosen. Dosage titration: Soliqua is to be dosed in accordance with the individual patient’s need for insulin.
Does Soliqua cause headaches?
General. The most commonly occurring adverse reactions with this combination drug include hypoglycemia, allergic reactions, nausea, nasopharyngitis, diarrhea, upper respiratory tract infection, and headache.
What are the side effects of metformin?
Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If stomach symptoms return later (after taking the same dose for several days or weeks), tell your doctor right away.
Is Trulicity insulin?
Trulicity is a non-insulin option that helps your body release the insulin it’s already making. In studies, Trulicity has been proven to lower blood sugar levels. People taking Trulicity may notice better blood sugar numbers before eating in the morning (fasting blood sugar).
What is Soliqua used for?
SOLIQUA 100/33 combines two medicines into one clinically proven treatment to help blood sugar control. If you’re taking oral diabetes medications or a long-acting insulin along with diet and exercise to try and lower your high A1c and not getting the results you want, your doctor may recommend SOLIQUA 100/33.
What is basal insulin?
What Is Basal Insulin? You may also hear it called background insulin. That’s what “basal” means. Your pancreas normally makes set amounts of insulin around the clock. Basal insulin mimics that process, and your body absorbs it slowly and uses it throughout the day.
Is Soliqua available in Canada?
Health Canada approves expanded indication for SOLIQUA® LAVAL, QC, Dec. 18, 2020 /CNW Telbec/ – Sanofi Canada announced that Health Canada has approved expanded use of SOLIQUA®.
What needles go with Soliqua?
Always use needles that are compatible with SOLIQUA 100/33. If you do not know which needles to use, ask your healthcare provider or pharmacist. NARRATOR VO: To attach the needle, keep the needle straight while you screw it onto the pen.
What are side effects of Ozempic?
The most common side effects of Ozempic® may include nausea, diarrhea, vomiting, stomach (abdominal) pain, and constipation. With any medicine, it’s very important to talk to your health care provider about side effects—talk to yours about any side effect that bothers you or doesn’t go away.
Is Ozempic daily?
Take Ozempic® once a week, on the same day every week, exactly as prescribed by your health care provider. You can take Ozempic® with or without food. You may change the day of the week you use Ozempic® as long as your last dose was taken 2 or more days before.
Why is Lantus given at night?
Lantus is designed to give a steady level of insulin over 24 hours, even when you are not eating such as between meals and overnight. This helps keep blood glucose levels consistent during the day and at night.
When should you not take Lantus?
Do not take Lantus during episodes of low blood sugar or if you are allergic to insulin or any of the inactive ingredients in Lantus. Do not share needles, insulin pens, or syringes with others.
Does Lantus lower blood sugar?
Lantus and Basaglar are both FDA-approved to lower blood sugar levels in adults and children with type 1 diabetes. They are also both approved to lower blood sugar levels in adults with type 2 diabetes. The use of Lantus and Basaglar for type 1 diabetes and type 2 diabetes has been directly compared.
Can federal employees use copay cards?
Yes. OPM does not prohibit FEHB members from participating in pharmacy-sponsored incentive or pharmaceutical company co-pay reimbursement programs, and we are unaware of any Federal laws restricting participation.
Can I get a 90 day supply of Clonazepam?
Some plans may require that you fill through a mail order pharmacy for fills of more than a 30-day supply. To switch to 90-day fills, note that you’ll need a new prescription from your doctor; a 30-day quantity prescription will not allow 90-day fills.