What causes Turners sign
Robert Spencer
Published Mar 03, 2026
The underlying cause of Grey Turner’s sign is generally thought to be abdominal hemorrhage (bleeding), the main source of which is commonly accepted as the pancreas. The cause of this bleeding is severe inflammation (swelling) due to infection, injury, or disease.
What is a positive Turner's sign?
Grey Turner’s sign is an uncommon subcutaneous manifestation of intra-abdominal pathology that manifests as ecchymosis or discoloration of the flanks. [1] Classically it correlates with severe acute necrotizing pancreatitis, often in association with Cullen’s sign (periumbilical ecchymosis).
What are Cullen and GREY Turner signs?
Cullen and Grey Turner signs indicate internal hemorrhage and warrant careful history-taking and investigations, including coagulation studies, serum lipase and amylase, and imaging. Cullen sign, first described in 1918, is superficial bruising in the subcutaneous fat around the umbilicus.
What does Cullens sign mean?
Cullen’s sign is described as superficial oedema with bruising in the subcutaneous fatty tissue around the peri-umbilical region. This is also known as peri-umbilical ecchymosis. It is most often recognised as a result of haemorrhagic pancreatitis.Where is the flank?
The flank is the area on the sides and back of your abdomen, between your lower ribs and your hips. Pain in this area is called flank pain.
How do you assess GREY Turner's sign?
Grey Turner’s signDifferential diagnosisAcute pancreatitis, ectopic pregnancy
What is the most common type of abdominal trauma?
[11] reported motor vehicle crashes (MVCs), fall from height and assaults to be the most common causes of blunt abdominal trauma. The penetrating trauma is mainly caused by gunshot, stab, and other objects that enter the peritoneal cavity.
What is necrotising pancreatitis?
Necrotizing pancreatitis (NP) is a health problem in which part of your pancreas dies. This is because of inflammation or injury. If the dead tissue gets infected, it can cause serious issues. The pancreas is an organ that sits behind your stomach. It makes fluids that flow through a duct into the small intestine.What is pseudo cyst?
A pseudocyst is a cystic lesion that may appear as a cyst on scans, but lacks epithelial or endothelial cells. An acute pancreatic pseudocyst is made of pancreatic fluids with a wall of fibrous tissue or granulation. Pseudocysts may form in a number of places, including the pancreas, abdomen, adrenal gland, and eye.
What organ is an inch above your belly button?By Marty Makary M.D., M.P.H. Located directly behind the stomach, the pancreas lies deep in the center of the abdomen. Its position corresponds to an area 3-6 inches above the “belly button”, straight back on the back wall of the abdominal cavity.
Article first time published onWhy is my belly button blue?
it is blue as that is the natural colour of the cotton which forms your clothing. the sweat caught in your belly-button helps the blue diffuse from the cotton into the fluff, giving the familiar sight.
What are flanks?
Flanks, or “love handles,” refer to the excess fat on the sides of your lower waist and back. Although excess can build up anywhere on the body, it often occurs in this area. That’s because the body tends to store fat around the belly.
What is hemorrhagic pancreatitis?
Acute hemorrhagic pancreatitis is defined by the disruption of the pancreatic microcirculation, which results in necrotizing pancreatitis. From: Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas (Second Edition), 2009.
What does bruising around the abdomen mean?
Bruising in your stomach or abdominal area is typically caused by: direct blows to your abdomen. a fall in which you injure or land on your stomach. accidents, such as a car accident.
What is Cullen?
Characterized by edema (swelling), bruising, and discoloration of the fatty tissue surrounding the umbilicus (navel), Cullen sign can arise due to pancreatitis (inflammation of the pancreas), cancer of the pancreas, ectopic pregnancy, liver problems, thyroid cancer, or other sources of internal bleeding in the abdomen.
What organ is right lower back?
The kidneys are located on either side of your spine, under your rib cage. Your right kidney hangs a little lower than the left, making it even more likely to cause lower back pain if it’s infected, irritated, or inflamed.
What kidney pains feel like?
Kidney pain is usually a constant dull ache deep in your right or left flank, or both flanks, that often gets worse when someone gently hits the area. Only one kidney is usually affected in most conditions, so you typically feel pain on only one side of your back.
What can be mistaken for kidney pain?
Kidney pain is felt in the sides or back. It is often mistaken for back pain. Kidney pain can be caused by kidney stones, urinary tract infection, kidney infection, an injury or kidney cancer.
Which organ is most likely to be injured blunt trauma?
Blunt abdominal trauma usually results from motor vehicle collisions (MVCs), assaults, recreational accidents, or falls. The most commonly injured organs are the spleen, liver, retroperitoneum, small bowel, kidneys (see the image below), bladder, colorectum, diaphragm, and pancreas.
Which hollow organ is most vulnerable to abdominal injuries?
Liver. The liver, the most vulnerable abdominal organ to all forms of injury because of its size and location (in the upper right quadrant of the abdomen), is injured in about five percent of all people admitted to a hospital for trauma.
Which organs are most often damaged with penetrating trauma?
The intestines were most commonly impacted by penetrating trauma (70.1% of cases), followed by the liver and spleen (19.4% and 17.9%, respectively). The most common mode of injury in penetrating trauma cases was gunshot (85%) and stab wounds (15%).
Why may Cullen and GREY Turner signs appear with acute pancreatitis?
Cullen’s sign and Grey Turner’s signs, described as ecchymosis about periumbilical area and in one or both flanks respectively, represent the extravasation of hemorrhagic pancreatic exudate to these areas. They occur in < 1% of individuals with acute pancreatitis and are associated with high mortality.
Is a Pseudocyst cancerous?
Pancreatic pseudocysts are rarely cancer. But they may need to be drained if you have pain or infection. Pancreatic pseudocysts are not the same thing as pancreatic abscesses. Abscesses also form during pancreatitis.
Can a person live without a pancreas?
It’s possible to live without a pancreas. But when the entire pancreas is removed, people are left without the cells that make insulin and other hormones that help maintain safe blood sugar levels. These people develop diabetes, which can be hard to manage because they are totally dependent on insulin shots.
How do you remove a pancreatic pseudocyst?
Treatments of pancreatic pseudocysts include conservative treatment (watchful monitoring), surgical drainage, which can be performed through a standard cut (open surgical drainage) or by key-hole surgery (laparoscopic surgical drainage), or endoscopic drainage.
What happens when your pancreas starts dying?
Sometimes people with severe acute pancreatitis can develop a complication where the pancreas loses its blood supply. This can cause some of the tissue of the pancreas to die (necrosis). When this happens, the pancreas can become infected, which can spread into the blood (sepsis) and cause organ failure.
Can a pancreas burst?
A pancreatic pseudocyst isn’t usually dangerous unless it ruptures. A ruptured pancreatic pseudocyst is a life-threatening condition. See your doctor immediately if you have any of the following symptoms: high, persistent fever.
What is end stage pancreatitis?
The end stage is characterized by steatorrhea and insulin-dependent diabetes mellitus. 6) Several characteristic complications of chronic pancreatitis are known such as common bile duct, duodenal, main pancreatic duct and vascular obstruction/stenosis.
What does pancreatic pain feel like?
The most common symptom of both acute and chronic pancreatitis is pain in the upper abdominal area, usually under the ribs. This pain: May be mild at first and get worse after eating or drinking. May become constant, severe, and last for several days.
Why is my stomach hard at the top?
When your stomach swells and feels hard, the explanation might be as simple as overeating or drinking carbonated drinks, which is easy to remedy. Other causes may be more serious, such as an inflammatory bowel disease. Sometimes the accumulated gas from drinking a soda too quickly can result in a hard stomach.
What does it mean when your stomach hurts under your ribs?
Gastritis refers to inflammation of the lining of your stomach, which is also near the left side of your rib cage. Other symptoms of gastritis include a burning pain in your stomach and an uncomfortable sense of fullness in your upper abdomen. Gastritis can be caused by: bacterial or viral infections.