How is sestamibi scan done
Rachel Hickman
Published Apr 07, 2026
When a sestamibi scan is performed, a state-of-the-art camera is used to identify the radioactive agent in the body. The camera is placed close to a patient’s head but won’t directly touch the head. A patient is asked to remain still as the camera captures images of the parathyroid glands.
How long does a sestamibi parathyroid scan take?
It takes approximately two hours to perform the Sestamibi scan after it has been injected. Pictures of the neck and chest are usually taken immediately after the injection and again in 1.75 to 2.0 hours (shown above).
How long does a nuclear medicine parathyroid scan take?
A parathyroid exam can take up to 4 or 5 hours. This time allows for two sets of images to be taken, with a 2.5 to 3.5 hour wait between sets. During your exam, a small amount of radioactive tracer will be injected into a vein in your arm.
How do I prepare for a sestamibi scan?
- Avoid caffeine for 24 hours before the test – caffeine may reduce the quality of the scan results (caffeine is in tea, coffee, cola and chocolate.
- Fast (not eat) for 4 hours before the test – but you can drink water.
How long does it take for results from a sestamibi scan?
Score of the ScanShows the TumorSame Patient Gets Scan Done by Dr Norman995%97%
Do you need to fast for parathyroid scan?
During the time between the scans you are free to leave the department and fasting is not necessary. Is there any preparation before this scan? There is no preparation for this scan. You may eat & drink as normal and are free to continue with any medication as prescribed by your doctor.
Can parathyroid glands be cancerous?
Parathyroid cancer is a rare disease in which malignant (cancer) cells form in the tissues of a parathyroid gland. The parathyroid glands are four pea-sized organs found in the neck near the thyroid gland.
Can a parathyroid tumor be mistaken for a thyroid nodule?
As neck ultrasonography is often used to make the differential diagnosis, parathyroid adenoma is sometimes mistaken for a thyroid nodule, resulting in the wrongful use of fine needle aspiration cytology [2].Can I eat before a parathyroid scan?
There is no special preparation necessary before the scan. You may eat and drink as normal.
Can I drive after a sestamibi scan?Are there any side effects of a Sestamibi Parathyroid Scan? There are no side effects of the injection. You will be able to drive, travel by public transport and return to work if necessary. You may experience a metallic taste in your mouth (but only for a few minutes) when you receive the radioisotope injection.
Article first time published onWhat medications should be delayed prior to a sestamibi?
In most cases, you can take your normal medications. However, there are various cardiac (heart) medications which you will need to discontinue (for two days prior to the test), including Isoptin and Beta Blockers (including Inderal, Betaloc, Lopressor, Aptin, Tenormin, Visken).
Does everyone have a parathyroid?
Everyone has four parathyroid glands, usually located right around the thyroid gland at the base of the neck. About 1 in 100 people (1 in 50 women over 50) will develop a parathyroid gland tumor during their lifetime, causing a disease called “hyperparathyroidism”.
How long is recovery from parathyroid surgery?
How Long Does It Take to Recover from Parathyroid Surgery? Parathyroid surgery recovery time varies, but most patients can resume their normal activities within a few days of treatment. Dr. Larian typically recommends his patients take up to five days off from work or school after a parathyroidectomy.
What's involved with a parathyroid scan?
A parathyroid scan uses a radioactive compound which gives off gamma rays, called a radiotracer, to diagnose and localize parathyroid adenoma. You will be given a small dose of radiotracer through an intravenous (IV). A gamma camera is used to detect the rays and produces images of parathyroid tissue.
Are parathyroid scans accurate?
The 4D Parathyroid CT scan is the newest imaging study to locate an abnormal parathyroid. It is the most accurate of the localization studies.
What happens if hyperparathyroidism is left untreated?
The effects of hyperparathyroidism can result in other health concerns, if left untreated. In addition to kidney stones and osteoporosis, older patients may physical symptoms including depression, mood changes, fatigue, muscle, and bone aches and pains, or even cardiac dysrhythmias.
What scan is used for hyperparathyroidism?
Four-dimensional parathyroid computed tomography (4DCT) is an advanced method for detecting enlarged parathyroid glands in the neck. Computed tomography, more commonly known as a CT or CAT scan, is a diagnostic medical imaging test.
What test is used for hyperparathyroidism?
Hyperparathyroidism is usually diagnosed with routine blood tests measuring the levels of parathyroid hormone (PTH), calcium and related minerals. Other possible tests and scans include: Urine Tests: Analyzing the urine during a 24-hour window can determine how much calcium the body is excreting.
Should you take vitamin D if you have hyperparathyroidism?
With care, vitamin D supplementation can safely be given to selected patients with asymptomatic primary hyperparathyroidism and is suggested before deciding on medical or surgical management. Monitoring serum calcium concentration and urinary calcium excretion is recommended while achieving vitamin D repletion.
What kind of doctor treats parathyroid issues?
Within the endocrine surgery community, a surgeon who performs 50 or more parathyroid operations per year is considered an expert parathyroid surgeon. These surgeons can be found through the American Association of Endocrine Surgeons (AAES).
Is parathyroid disease fatal?
The simple answer is this: yes. Having high calcium in your blood is much more dangerous than having high cholesterol. Having high blood calcium is more deadly than having thyroid cancer. In fact, having a parathyroid tumor caries the same risk of early death as having diabetes.
How long does a parathyroid ultrasound take?
The test takes about 30 minutes. You may be asked to wait until the radiologist has reviewed the information. The radiologist may want to do more ultrasound views of your neck.
How much radiation is in a sestamibi scan?
The mean radiation dose of dynamic parathyroid CT was 5.56 mSv, while sestamibi scintigraphy delivered a mean radiation dose of 3.33 mSv (P < . 05).
How is scintigraphy done?
Scintigraphy is used to diagnose, stage, and monitor disease. A small amount of a radioactive chemical (radionuclide) is injected into a vein or swallowed. Different radionuclides travel through the blood to different organs.
Does parathyroid cause cough?
Infrequently, parathyroid adenomas can present with rare signs and symptoms due to pressure effect on surrounding structures, e.g. esophagus causing dysphagia or trachea causing dyspnea or chronic cough due to pressure on recurrent laryngeal nerve.
Can you feel a parathyroid tumor when you swallow?
Dysphagia, neck discomfort and sore throat are among common symptoms of parathyroid adenoma. Reports reveal that pain, swelling, tenderness in anterior neck, dysphagia, hoarseness, and ecchymosis are among the usual presentations of parathyroid adenoma.
What are the symptoms of parathyroid tumor?
- Aches and pains, especially in your bones.
- Kidney problems, including pain in your upper back or side.
- Depression.
- Stomach pain.
- Loss of appetite and intense thirst.
- Nausea.
- Vomiting.
- Fatigue.
What does hyperparathyroidism cause?
Too much PTH causes calcium levels in your blood to rise too high, which can lead to health problems such as bone thinning and kidney stones. Doctors usually catch primary hyperparathyroidism early through routine blood tests, before serious problems occur.
How do you detox after a nuclear stress test?
You will need to do the following: Drink plenty of liquids as directed. This will help flush the radioactive liquid out of your body. Ask how much liquid to drink each day and which liquids are best for you.
What should I avoid after a nuclear stress test?
Caffeine can alter the test results. Do not eat chocolate or drink coffee, tea, soda, colas or other caffeinated beverages such Mountain Dew or energy drinks. If you are unsure, do not drink it. See the table below for more details.
What is a normal summed rest score?
Summed stress scores of less than 3 are considered normal, whereas scores of 4–7, 8–12, and 13 or higher are indicative of low, intermediate, and high risk for a hard cardiac event. When a perfusion defect is identified, its location, size, severity, and reversibility must be reported.